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M A T E R I A L S A F E T Y D A T A S H E E T VASOPRESSIN ================================================================================ SECTION I - Product Identification ================================================================================ PRODUCT NAME: VASOPRESSIN COMPANY NAME: SIGMA CHEMICAL COMPANY DATE: 02/13/89 EMERGENCY TELEPHONE: (314) 771-5765 RTECS: YW8659000 CAS #: 50-57-7 SYNONYMS: DIAPID; LYPRESSIN; LYSINE PITRESSIN; LYSINE VASOPRESSIN; POSTACTON; SYNTOPRESSIN; VASOPHYSIN; ================================================================================ SECTION II - Hazardous Components ================================================================================ NDA ================================================================================ SECTION III - Physical Data ================================================================================ MP: NDA BP: NDA APPEARANCE & ODOR: CLEAR COLORLESS LIQUID SOLUBILITY: WATER-SOLUBLE ================================================================================ SECTION IV - Fire and Explosion Hazard Data ================================================================================ FLASHPOINT: NDA EXTINGUISHING MEDIA: NON-COMBUSTIBLE. USE EXTINGUISHING MEDIA APPROPRIATE TO SURROUNDINGS. SPECIAL FIREFIGHTING PROCEDURES: WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO PREVENT CONTACT WITH SKIN AND EYES. UNUSUAL FIRE AND EXPLOSION HAZARDS: NDA ================================================================================ SECTION V - Health Hazard Data ================================================================================ ACUTE EFFECTS: MAY BE HARMFUL BY INHALATION, INGESTION, SKIN ABSORPTION. CAUSES EYE AND SKIN IRRITATION. EXPOSURE CAN CAUSE NASAL CONGESTION WITH ULCERATION OF NASAL MUCOSA, HEADACHE, CONJUNCTIVITIS, HEARTBURN, SUBSTERNAL TIGHTNESS, COUGHING, AND TRANSIENT DYSPNEA. HYPERSENSITIVITY REACTIONS ARE LESS WITH SYNTHETIC LYPRESSIN THAN WITH OTHER FORMS OF VASOPRESSIN. TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL/PHYSICAL/TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED. FIRST AID PROCEDURES: IMMEDIATELY FLUSH EYES OR SKIN WITH COPIOUS AMOUNTS OF WATER FOR AT LEAST 15 MINUTES; ASSURE ADEQUATE FLUSHING BY SEPARATING EYELIDS WITH FINGERS. IF INHALED, REMOVE TO FRESH AIR. IF BREATHING IS DIFFICULT, CALL A PHYSICIAN. INGESTION: WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS. CALL A PHYSICIAN !!! CONTAMINATED CLOTHING & SHOES: REMOVE. ================================================================================ SECTION VI - Reactivity Data ================================================================================ STABILITY: STABLE HAZARDOUS COMBUSTION: CARBON MONOXIDE, CARBON DIOXIDE NITROGEN OXIDES SULFUR OXIDES HAZARDOUS POLYMERIZATION: WILL NOT OCCUR INCOMPATIBILITIES: NDA ================================================================================ SECTION VII - Spill and Disposal Procedures ================================================================================ SPILLED MATERIAL: EVACUATE AREA. SHUT OFF ALL SOURCES OF IGNITION. WEAR CHEMICAL SAFETY GOGGLES, RUBBER BOOTS, HEAVY RUBBER GLOVES. WEAR SELF-CONTAINED BREATHING APPARATUS. AVOID RAISING DUST. VENTILATE AREA & WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE. ABSORB ON SAND OR VERMICULITE AND PALCE IN CLOSED CONTAINERS FOR DISPOSAL. DISPOSAL: INCINERATOR CHEMICAL INCINERATOR EQUIPPED WITH AN AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL LAWS. ================================================================================ SECTION VIII - Protective Equipment ================================================================================ EYES: SAFETY GOGGLES SKIN: CHEMICAL RESISTANT GLOVES, CLOTHING VENTILATION: MECHANICAL EXHAUST RESPIRATOR: NIOSHA/MSHA-APPROVED RESPIRATOR OTHER: SAFETY SHOWER AND EYE WASH. FULL PROTECTIVE CLOTHING. ================================================================================ SECTION IX - Storage and Handling Precautions ================================================================================ STORAGE PRECAUTIONS: DO NOT GET IN EYES, SKIN, CLOTHING. DO NOT PIPET BY MOUTH. DO NOT BREATHE VAPOR. KEEP TIGHTLY CLOSED. WASH THOROUGHLY AFTER HANDLING. ================================================================================ SECTION X - Transportation Data and Additional Information ================================================================================ TOXICITY DATA: ORL-RAT LD50 (MG/KG): NDA IHL-RAT LD50 (PPM): NDA SKN-RBT LD50 (MG/KG): NDA ORL-HMN LD5O (MG/KG): NDA -------------------------------------------------------------------------------- (TM) and (R) : Registered Trademarks N/A = Not Applicable OR Not Available The information published in this Material Safety Data Sheet has been compiled from our experience and data presented in various technical publications. It is the user's responsibility to determine the suitability of this information for adoption of necessary safety precautions. We reserve the right to revise Material Safety Data Sheets periodically as new information becomes available. Copyright by Manufacturer